Evaluation for MTBI and DAI by using Voxel-Based Diffusion Tensor Imaging

Introduction: In Japan, there are approximately 280,000 new cases of traumatic brain injury (TBI) each year, with at least 80% being classified as mild. The diagnosis and management of mild traumatic brain injury (MTBI) continues to be the subject of debate, with varying opinions regarding the extent to which organically based impairments vs the impact of other stressors cause ongoing disability. Detecting areas of the brain with abnormalities that can explain symptoms and behavior in patients with MTBI is important in order to confirm the diagnosis of MTBI. Several studies have recently reported the effectiveness of diffusion-weighted imaging (DWI) for evaluation of diffuse axonal injury (DAI) and MIBI. Diffusion tensor imaging (DTI), a relatively novel MRI technique, is designed to detect more extensive abnormalities than conventional MRI in patients with severe head injury, and the findings of DTI have been reported to correspond with clinically determined neurological deficit. In this study, we make the apparent diffusion coefficient (ADC, λ ⊥ , and λ ∥ )) maps and the fractional anisotropy (FA) maps calculated from DTI in control group. And we compared each maps in MIBI group and DAI group with these.